What main feature distinguishes chronic inflammatory skin disorders like acne?

The main feature that distinguishes chronic inflammatory skin disorders like acne is the presence of comedones and blemishes. Comedones, which can be open (blackheads) or closed (whiteheads), are a result of clogged hair follicles due to excess sebum production and dead skin cells. Inflammatory responses in acne lead to the formation of papules, pustules, and sometimes nodules, which collectively are referred to as blemishes.

Recognizing this feature is essential for identifying and treating acne effectively. Treatments often aim to reduce the formation of comedones and inflammation to improve the skin's appearance and health. Other features commonly associated with skin conditions do not apply specifically to acne, making the identification of comedones and blemishes the hallmark sign of this chronic inflammatory disorder.